Supramolecular Hydrogels Based on Nanoclay and Guanidine-Rich Chitosan: Injectable and Moldable Osteoinductive Carriers
نویسندگان
چکیده
منابع مشابه
Hydrogels in calcium phosphate moldable and injectable bone substitutes: Sticky excipients or advanced 3-D carriers?
The combination of hydrogels and calcium phosphate particles is emerging as a well-established trend for bone substitutes. Besides acting as binders for the inorganic phase, hydrogels within these hybrid materials can modulate cell colonization physically and biologically. The influence of hydrogels on the healing process can also be exploited through their capability to deliver drugs and cells...
متن کاملFabrication of injectable hydrogels based on poly(l-glutamic acid) and chitosan
Injectable hydrogels as an important biomaterial class have been widely used in regenerative medicine. A series of injectable poly(L-glutamic acid)/chitosan (PLGA/CS) hydrogels were fabricated by selfcrosslinking aldehyde-modified PLGA (PLGA–CHO) and lactic acid-modified chitosan (CS–LA). The oxidation degree of PLGA–CHO and degree of substitution (DS) of CS–LA could be adjusted by the amount o...
متن کاملVancomycin-loaded HPMC microparticles embedded within injectable thermosensitive chitosan hydrogels
Antibiotic use is an essential method for the treatment of bacterial infections. In certain cases, antibiotics are not effective because of the distribution problems caused by physiological barriers in the body. Such problems are thought to be minimized by development of sustained release systems which involve implantation of antibiotic loaded polymeric systems directly to the site of infection...
متن کاملNear infrared light-responsive and injectable supramolecular hydrogels for on-demand drug delivery.
A near infrared (NIR) light-responsive supramolecular hydrogel consisting of α-cyclodextrin and poly(ethylene glycol)-modified dendrimer-encapsulated platinum nanoparticles was developed. Upon NIR irradiation, this hydrogel underwent a photothermo-sensitive degradation to release the entrapped therapeutic agents in an on-demand and dose-tunable fashion.
متن کاملInjectable Hydrogels: A Review of Injectability Mechanisms and Biomedical Applications
Hydrogels have been used for biomedical applications in recent decades. They are a perfect candidate for regenerative medicine as they resemble the extracellular matrix of native tissues. In addition, their highly hydrated structure makes them a suitable choice for drug and other therapeutics delivery. Injectable hydrogels have increasingly gained attention due to their capability for homogeneo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Applied Materials & Interfaces
سال: 2020
ISSN: 1944-8244,1944-8252
DOI: 10.1021/acsami.0c01241